Pompey Academy’s under-18 side will begin the season with a home match against Sheffield Wednesday at the Wellington Sports Ground on Saturday, August 21.
Paul Smalley's side are in Group A of the Premier Academy League, alongside Arsenal, Charlton, Chelsea, Crystal Palace, Fulham, Ipswich, Norwich, Southampton and West Ham.
The Blues will play each of the sides in their group home and away, as well as 10 matches against sides from other groups.
Those extra matches are against Sheffield Wednesday, Nottingham Forest, Aston Villa, Watford, Leicester, Bristol City, Reading, Birmingham, MK Dons and Cardiff.
Pompey Academy 2010/11 fixtures:
Sat Aug 21 Sheffield Wednesday (H)
Sat Aug 28 Nottingham Forest (A)
Sat Sep 4 Aston Villa (H)
Sat Sep 11 Watford (A)
Sat Sep 18 Leicester City (H)
Sat Sep 25 Charlton Athletic (A)
Sat Oct 2 Fulham (H)
Sat Oct 9 Norwich City (A)
Sat Oct 16 Crystal Palace (A)
Sat Oct 30 Ipswich Town (H)
Sat Nov 6 Arsenal (A)
Sat Nov 13 West Ham United (H)
Sat Nov 20 Chelsea (H)
Sat Dec 4 Southampton (A)
Sat Dec 11 Crystal Palace (H)
Sat Jan 8 Ipswich Town (A)
Sat Jan 15 Arsenal (H)
Sat Jan 22 West Ham United (A)
Sat Feb 5 Chelsea (A)
Sat Feb 12 Southampton (H)
Sat Feb 19 Charlton Athletic (H)
Sat Feb 26 Fulham (A)
Sat Mar 5 Norwich City (H)
Sat Mar 12 Bristol City (A)
Sat Mar 19 Reading (H)
Sat Mar 26 Birmingham City (A)
Sat Apr 9 Milton Keynes Dons (H)
Sat Apr 30 Cardiff City (A)