Cooper, Painter and N'Gala also come into the side
David Connolly returns to the Pompey side to face Fleetwood this afternoon.
The striker is available again after a three-match suspension and is one of four changes from the side that won at Burton last week.
Marcos Painter, Bondz N’Gala and Shaun Cooper also start in a new-look Blues defence.
Yassin Moutaouakil starts a three-match ban, while Joe Devera is out with a hamstring injury.
Jed Wallace and Danny East drop to the bench, where they are joined by new loan signing John Marquis.
Pompey: Sullivan; Cooper, N’Gala, Bradley, Painter; Holmes, Ertl (c), Ferry, Barcham; Agyemang, Connolly
Subs: Smith, Butler, East, Wallace, Padovani, Craddock, Marquis