For the third away match in succession, Pompey will be appearing in front of the Sky Sports cameras this weekend.
The previous two have provided mixed emotions, with the Blues letting a three-goal lead slip to draw with Southend, before a 3-0 victory at Bury secured a spot at Wembley.
It is Charlton who host the latest televised encounter, which sees a clash between the sides sitting fifth and fourth in League One.
Kenny Jackett’s troops currently hold a five-point advantage over the Londoners, with both clubs having 11 games remaining.
That is the same difference that currently separates Pompey from the second automatic promotion spot.
The Addicks are playing their third campaign at this level following relegation in 2016 and were beaten by Shrewsbury in the play-offs last term.
Charlton were 2-1 victors when the sides met at Fratton Park in December, with Andre Green grabbing a late consolation before Ben Thompson was sent off – a decision that was successfully appealed.
But the Blues have won 1-0 on each of their past three visits to The Valley, including last season’s league clash which was settled by a Josh Magennis own-goal.
Matt Clarke, Ronan Curtis, Oli Hawkins and Nathan Thompson are all available, despite limping off the field last Saturday.
Omar Bogle (hamstring) is a doubt, while Andy Cannon (quad), Bryn Morris (knee) and Jack Whatmough (knee) are definitely out.
Former Pompey defender Jason Pearce is missing for the hosts with an ankle problem and Charlton boss Lee Bowyer is currently serving a touchline ban.
HEAD TO HEAD
Pompey: 45 wins
Charlton: 35 wins
Pompey: 18 wins
Charlton: 19 wins
Pompey have sold their full allocation of more than 3,000 tickets and no more will be available.
The game has been selected for live television coverage, so there will be no live video on iFollow for overseas subscribers.
Viewers in the UK can watch the game live on Sky Sports Football, while overseas supporters should check their local listings.
ALSO IN LEAGUE ONE
Kick-off 3pm unless stated
Coventry v Burton (7.45pm)
AFC Wimbledon v Doncaster
Barnsley v Accrington
Blackpool v Southend
Bradford v Peterborough
Gillingham v Oxford
Plymouth v Luton
Rochdale v Shrewsbury
Scunthorpe v Bristol Rovers
Walsall v Fleetwood
Wycombe v Sunderland
LAST MEETING AT THE VALLEY