The latest international break threatened to leave Pompey with yet another blank weekend in this stop-start season.
But the Blues made the decision to go ahead with Saturday’s fixture against Gillingham and try to build some more momentum.
Back-to-back victories over Bolton and Doncaster mean that Kenny Jackett’s side are slowly starting to climb the League One standings.
But they will be targeting higher than their current position of 16th, which is one place and one point behind this weekend’s Fratton visitors.
The Gills – who appointed Steve Evans as boss over the summer – have played two more matches than their hosts.
They enjoyed a relatively comfortable 3-1 victory over struggling Southend last Saturday, with former Pompey loanee Stuart O’Keefe among the scorers.
It was not a happy day for every member of the Kent outfit, however, as Mikael Ndjoli hit the post with one penalty and saw another saved.
They were, like the Blues, in Leasing.com Trophy action during the week, although a much-changed side were thrashed 4-0 at Ipswich.
Gillingham have yet to win on their travels so far this term, but have tasted success in each of their past two league visits to Fratton Park.
Pompey are without first choice keeper Craig MacGillivray and midfielder Ross McCrorie, who are away on Scottish international duty.
Ronan Curtis withdrew from the Republic of Ireland squad with a tight hamstring, but has recovered and been given the green light to feature.
Tom Naylor and John Marquis have both recovered from knocks, with Oli Hawkins (foot), Bryn Morris (groin) and Jack Whatmough (knee) all sidelined.
Both sides are likely to make multiple changes after resting key players for Leasing.com Trophy matches during the week.
HEAD TO HEAD
Pompey: 19 wins
Gillingham: 9 wins
At Fratton Park
Pompey: 12 wins
Gillingham: 2 wins
Pompey fans can secure their seat online here or by visiting the Anson Road ticket office.
Subject to availability, they can also be bought from both ticket offices from 9am on Saturday.
Referee: Graham Salisbury
Assistants: Christopher Wade and Paul Kelly
Fourth Official: Lee Collins
Overseas subscribers and match pass holders can watch the action and commentary will begin from around 10 minutes before kick-off.
ALSO IN LEAGUE ONE
Kick-off 3pm unless stated
Blackpool v Rotherham
Bristol Rovers v MK Dons
Oxford v Doncaster
Peterborough v Lincoln
Rochdale v Accrington
Southend v AFC Wimbledon
Coventry v Tranmere (12pm)