Pompey will aim to stretch their winning run to five games when they host Burton on Saturday (3pm kick-off).
Ipswich, Shrewsbury, Rochdale and Wigan have all been seen off since Danny Cowley was appointed head coach last month.
It leaves the Blues sitting fourth in the League One standings and with a five-point buffer to Charlton, who are located just outside the play-off positions.
Their next opponents recently enjoyed their own run of six successive victories and recovered from a leaner spell to beat Swindon on Easter Monday.
They were bottom of the table and apparently doomed to relegation when Jimmy Floyd Hasselbaink was reappointed manager at the turn of the year.
But the man who previously guided the Brewers to League Two promotion before departing for QPR in 2015 has once again shown the Midas touch.
Their remarkable form in 2021 has led the side out of the relegation places and to a more comfortable 18th spot.
All four previous Fratton Park meetings between the teams have ended in a draw, but a Marcus Harness hat-trick helped Pompey secure a 4-2 victory at the Pirelli Stadium earlier in the season.
John Marquis will be forced to sit out again, with the striker completing his three-match ban for a red card at Shrewsbury.
Sean Raggett is a doubt after injuring his cheekbone at Wigan on Monday, while Alex Bass (foot), Ellis Harrison (knee) and Jordy Hiwula (ankle) remain sidelined.
Burton defender Kieran Wallace is out for the remainder of the season after suffering a serious knee injury in February.
Loan duo Sean Clare and Jonny Smith are also carrying knocks for the Brewers and will undergo fitness tests.
HEAD TO HEAD
Pompey: 3 wins
Burton: 1 win
At Fratton Park
Pompey: 0 wins
Burton: 0 wins
Referee: John Busby
Assistants: Mark Derrien and Justin Amey
Fourth Official: Carl Brook
Supporters in the UK can watch the action live – with graphics, commentary and replays – by purchasing a match pass for £10.
Please note that subscribers based in the UK and Ireland will still need to purchase a match pass in order to watch the game live.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
ALSO IN LEAGUE ONE
All games kick-off at 3pm
Accrington v AFC Wimbledon
Crewe v Oxford
Doncaster v Wigan
Fleetwood v Rochdale
Gillingham v Shrewsbury
Ipswich v MK Dons
Lincoln v Blackpool
Northampton v Bristol Rovers
Plymouth v Hull
Sunderland v Charlton
Swindon v Peterborough