Pompey’s hopes of sneaking into the play-off places came to an end on Monday, with three games of the season remaining.
But they have a fine home record to defend when Gillingham visit Fratton Park on Saturday (3pm kick-off).
There is more on the line for the visitors, who are currently perched precariously just above the League One drop zone.
The Kent outfit are in 20th position and have only a single point more than Fleetwood, who hold both a game in hand and a superior goal difference.
Those two sides played out a goalless draw at Priestfield Stadium on Easter Monday to ensure it remains incredibly tight at the bottom of the table.
The Gills have improved since Neil Harris replaced Steve Evans as manager in January and have lost just one of their past six games – although four of them ended all square.
A deflected Michael Jacobs strike deep into stoppage-time separated the sides earlier in the campaign.
It finished 1-1 in the most recent contest at Fratton Park last February, with Sean Raggett’s opener cancelled out by Vadaine Oliver.
Kieron Freeman (ankle), Reeco Hackett (knee) and Jayden Reid (knee) are all still sidelined for Pompey.
Midfielder Joe Morrell is likely to be available again after missing the Morecambe trip with a dead leg.
Robbie McKenzie and former Fratton loanee Stuart O’Keefe are both doubts for the visitors after going off injured against Fleetwood on Monday, with Mustapha Carayol (hamstring) definitely missing.
Striker Charlie Kelman was sent off in that contest, although Gillingham were considering launching an appeal.
HEAD TO HEAD
Pompey: 21 wins
Gillingham: 9 wins
At Fratton Park
Pompey: 12 wins
Gillingham: 2 wins
Click here to see what is happening around the ground on Saturday, including the return of former players, a Player of the Season presentation and post-match live music.
Referee: Darren Drysdale
Assistants: Paul Kelly and Robert Dabbs
Fourth Official: Daniel Cook
Overseas subscribers and match pass holders can watch all the action live, with accompanying commentary.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
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ALSO IN LEAGUE ONE
All games kick-off at 3pm
Accrington v Lincoln
Charlton v Shrewsbury
Cheltenham v Bolton
Crewe v Ipswich
Doncaster v Burton
Fleetwood v AFC Wimbledon
MK Dons v Morecambe
Rotherham v Oxford
Sunderland v Cambridge
Wigan v Plymouth
Wycombe v Sheffield Wednesday