Pompey begin a long run of away games when they visit the Keepmoat Stadium to take on Doncaster on Saturday (3pm kick-off).
The postponement of a Fratton fixture with Plymouth at the start of September means the next three league contests are all on the road.
Danny Cowley’s side are hoping to build on their perfect beginning to the campaign, with three successive victories sending them to the League One summit.
Their next opponents, by contrast, are one of a trio of teams yet to collect a single point so far this term.
Rovers have been beaten by AFC Wimbledon, Sheffield Wednesday and Accrington, although did see off Walsall on penalties to reach the second round of the Carabao Cup.
Former Salford boss Richie Wellens took charge of the South Yorkshire outfit in May following the departure of Darren Moore a couple of months earlier.
One of his first acts as manager was to persuade Ben Close to turn down a new contract at Fratton Park and sign for Doncaster.
A last-gasp John Marquis goal was not enough to prevent the Blues from losing 2-1 in last season’s corresponding fixture.
Pompey have doubts over the fitness of Marcus Harness (quad) and skipper Clark Robertson (ankle) after the pair went off injured at half-time on Tuesday night.
Jayden Reid (knee) and Liam Vincent (shin) are definitely missing, while Callum Johnson serves the final game of his suspension.
Former Pompey forward Jordy Hiwula is sidelined for Doncaster, along with Fejiri Okenabirhie and Jon Taylor (all ankle).
Charlie Seaman and Matt Smith are both back in training after periods of self-isolation, with the latter having contracted Covid-19 and the former deemed a close contact.
HEAD TO HEAD
Pompey: 11 wins
Doncaster 8 wins
Pompey: 6 wins
Doncaster: 4 wins
Referee: Carl Boyeson
Assistants: Mark Cunliffe and Joe Simpson
Fourth Official: Stephen Wade
Overseas subscribers and match pass holders can watch the action and commentary will begin from around 10 minutes before kick-off.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
ALSO IN LEAGUE ONE
Games kick-off at 3pm unless stated
Rotherham v Sheffield Wednesday (1pm)
Bolton v Oxford
Cambridge v Burton
Charlton v Wigan
Crewe v Accrington
Fleetwood v Cheltenham
Gillingham v Morecambe
Ipswich v MK Dons
Shrewsbury v Plymouth
Sunderland v AFC Wimbledon
Wycombe v Lincoln