Pompey make the long trip north for a second successive weekend when they visit Wigan on Saturday (3pm kick-off).
Danny Cowley’s side saw their 100 per cent winning record ended by a goalless draw at Doncaster last time out.
But another shut-out means the Blues are one of just two sides – along with League One leaders Sheffield Wednesday – yet to concede in the entire EFL.
Their next opponents were beaten at Sunderland on the opening day, but have gone on to enjoy win over Rotherham and Charlton, as well as a draw with Wycombe.
Leam Richardson’s troops also beat both Hull and Bolton to reach the third round of the Carabao Cup, where they will lock horns with the Black Cats once more.
Wigan exited administration towards the end of last season and survived the drop by just a single point.
And they have worked hard to revamp their squad over the summer, with 13 new players coming through the door.
Both sides won on each other’s patch during the 2020/21 campaign, as a strike from substitute Andy Cannon was enough to secure Pompey the points at the DW Stadium on Easter Monday.
Pompey are sweating over the fitness of Marcus Harness (quad), while Jayden Reid (knee) and Liam Vincent (shin) are definitely missing.
Tom Naylor and Jack Whatmough are both expected to feature against their former club for Wigan, who could hand a debut to Tom Bayliss.
HEAD TO HEAD
Pompey: 11 wins
Wigan: 6 wins
Pompey: 5 wins
Wigan: 3 wins
Pompey fans can purchase tickets (cash only) at the DW Stadium ticket office on the day of the game.
Referee: Christopher Sarginson
Assistants: Mark Russell and George Byrne
Fourth Official: Robert Massey-Ellis
Overseas subscribers and match pass holders can watch the action and commentary will begin from around 10 minutes before kick-off.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
ALSO IN LEAGUE ONE
Games kick-off at 3pm unless stated
Burton v Cheltenham (7.45pm)
Rotherham v Doncaster (1pm)
Cambridge v Bolton
Charlton v Crewe
Ipswich v AFC Wimbledon
MK Dons v Accrington
Morecambe v Sheffield Wednesday
Oxford v Lincoln
Plymouth v Fleetwood
Shrewsbury v Gillingham
Sunderland v Wycombe