Pompey saw their 10-game unbeaten run in League One ended by MK Dons at Fratton Park at the weekend.
So now Danny Cowley’s men will look to start a new one when they visit AFC Wimbledon this evening (7.45pm kick-off).
The fixture was originally scheduled to take place a week before Christmas, but had to be postponed because of a Covid outbreak in the Blues squad.
It will be the third meeting between the sides this season, with goals from Michael Jacobs and Marcus Harness ensuring the hosts came from behind to win the reverse fixture back in November.
There was also a contest at Plough Lane in the Papa John’s Trophy, when Ellis Harrison – who has since left the south coast – bagged a hat-trick in a 5-3 defeat.
The Dons currently sit 20th in the League One standings and are one place – and two points – above the drop zone.
Mark Robinson’s side do, however, have at least two games in hand on all the sides around them in the table.
They drew 0-0 at home with Morecambe on Saturday to end a run of three successive losses, which included an FA Cup exit at the hands of non-league Boreham Wood.
Pompey have no new injury worries, with Liam Vincent (shin) and Jayden Reid (knee) the only absentees.
John Marquis has left the club to sign for Lincoln, but defender Hayden Carter could make his debut after arriving on loan from Blackburn.
Nesta Guinness-Walker is available again for the hosts after serving a one-match ban, but Ben Henghan has tested positive for Covid-19.
AFC Wimbledon will also be without Paul Kalambayi (knee), Henry Lawrence (hamstring) and Aaron Pressley (hamstring), while Anthony Hartigan is a doubt.
VIEW FROM THE DRESSING ROOM
Read the thoughts of Danny Cowley ahead of the game.
HEAD TO HEAD*
Pompey: 19 wins
Wimbledon: 15 wins
On the road
Pompey: 7 wins
Wimbledon: 11 wins
*Includes matches against Wimbledon FC
Pompey fans have snapped up their full allocation of tickets and no more will be made available.
Supporters travelling to the game should wear a face mask in all indoor areas, while there will be Covid certification spot checks.
If approached, you will be asked to show proof of double vaccination or a negative lateral flow test. Please note that you will not be refused entry if you are unable to show this.
Referee: James Oldham
Assistants: Nicholas Cooper and Kevin Howick
Fourth Official: Adrian Tranter
Overseas subscribers and match pass holders can watch the action and commentary will begin from around 10 minutes before kick-off.
Please note that the decision to broadcast displaced weekend matches to supporters in the UK and Ireland is made by the home club and AFC Wimbledon have opted not to utilise this service.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Wednesday.
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ALSO IN LEAGUE ONE
All games kick-off at 7.45pm
Cambridge v Doncaster
Morecambe v Wigan
Rotherham v Lincoln
LAST AWAY LEAGUE MEETING