Pompey are on the road for the final time this season when they visit Derby on Saturday (3pm kick-off).
With John Mousinho’s men now unable to reach the top six, pride is all that is at stake for the Blues, who will be backed by more than 3,000 supporters at Pride Park.
It is a much more crucial contest for the hosts, who currently occupy the final League One play-off spot.
The Rams are below fifth-placed Bolton on goal difference, with the pair both trying to hold off Peterborough, who sit two points further back in seventh.
Paul Warne’s side go into the contest on a five-match unbeaten run, which includes narrow wins in their two most recent fixtures against Exeter and Burton.
And they will be particularly keen for a win in their final home match, as the final day sees them visit a Sheffield Wednesday outfit who could still be in the hunt for automatic promotion.
Derby are looking to make an immediate return to the Championship after suffering relegation under Wayne Rooney’s leadership last term.
That came amidst financial turmoil, with the club only going down because they were deducted a total of 21 points for entering administration and breaching accounting rules.
It finished goalless when the sides met at Fratton Park earlier in the campaign, while Pompey were beaten 3-1 on their last visit to Pride Park for a second tier contest in October 2011.
Ronan Curtis (knee) and Jayden Reid (knee) are both missing, while Zak Swanson (groin) is unlikely to feature in the final two games after returning to training following a groin problem.
Denver Hume (knee) is also a doubt, but Joe Morrell is available again after completing a four-match ban.
James Chester (calf) and Tony Springett (ankle) are both missing for Derby, whose matchday squad will likely include former Pompey players Luke McGee, Nathaniel Mendez-Laing and Harvey White.
HEAD TO HEAD
Pompey: 35 wins
Derby: 42 wins
On the road
Pompey: 10 wins
Derby: 29 wins
Pompey fans will not be able to purchase tickets on the day of the game, so please do not travel without one.
Click here to read a guide to visiting Pride Park that has been produced by the home club.
Referee: Lee Swabey
Assistants: Robert Atkin and Sian Massey-Ellis
Fourth Official: Sam Purkiss
Overseas subscribers and match pass holders can watch all the action live, with accompanying commentary.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
ALSO IN LEAGUE ONE
All games kick-off at 3pm
Accrington v Cambridge
Bolton v Fleetwood
Charlton v Port Vale
Forest Green v Oxford
Ipswich v Exeter
MK Dons v Barnsley
Morecambe v Lincoln
Peterborough v Bristol Rovers
Plymouth v Burton
Shrewsbury v Sheffield Wednesday
Wycombe v Cheltenham