Back the Blues with Sky Bet
Pompey opened their league campaign by coming from behind to pick up a point at Exeter.
But there was more joy for Cambridge, who celebrated their return to the Sky Bet Football League after a nine-year absence with victory over Plymouth.
The hosts are even money for victory this weekend, however, while United can be backed at 13/5. The draw is available at 12/5.
Ryan Taylor and Craig Westcarr lead the first goalscorer market at 5/1 each, with Tuesday night's cup goal hero Miles Storey at 6/1.
Under 2.5 goals is 8/11 and that bet would have been landed in both teams’ opening fixtures.
A goalless draw comes in at 17/2, but those expecting the keepers to be kept busy might want to consider the 20/1 that both sides score in each half.
Top tip: Both teams to score in the first half at 4/1.
Sky Bet are the title sponsor of The Football League. This season, a £250,000 Sky Bet Transfer Fund will go to a Football League club to spend on players in the January 2015 transfer window.
Fans who bet with Sky Bet generate Transfer Fund Tokens and go into a random draw to win a £5,000 prize – and the £250,000 Sky Bet Transfer Fund for their Football League club.
To sign up, go to www.skybet.com/pompey and follow the instructions.