Back the Blues with Sky Bet
Fourth from bottom plays host to fourth from top at the Kassam Stadium this weekend.
Visitors Pompey are 7/5 favourites with Sky Bet to walk away with all three points, while Oxford can be backed at 15/8 and the draw is 23/10.
Craig Westcarr tops the first goalscorer market at 5/1, with United duo Danny Hylton and Carlton Morris are both available at 6/1.
Goals have been the main problem for Oxford so far this season and a low-scoring encounter could be on the cards.
Top Tip: Under 1.5 goals at 9/4
Sky Bet are the title sponsor of The Football League. This season, a £250,000 Sky Bet Transfer Fund will go to a Football League club to spend on players in the January 2015 transfer window.
Fans who bet with Sky Bet generate Transfer Fund Tokens and go into a random draw to win a £5,000 prize – and the £250,000 Sky Bet Transfer Fund for their Football League club.
To sign up, go to www.skybet.com/pompey and follow the instructions.