All you need to know about League Two clash
Andy Awford is about to return to Fratton Park for the first time since he departed as manager back in April.
The Pompey Hall of Fame inductee – who made more than 370 appearances for the club – has been in caretaker charge of Luton since they sacked John Still before Christmas.
He led the Hatters to a 3-2 victory at Exeter in his first match as boss, courtesy of a winner from former Blues loanee Paul Benson in the 10th minute of stoppage-time.
But, like Pompey, they were beaten on Boxing Day, going down 2-0 to Wycombe on their own patch.
That leaves Luton sitting 15th in the League Two table – 16 points clear of the bottom two and eight adrift of the play-off spots.
Matt Tubbs grabbed a late winner when Paul Cook’s side won 2-1 at Kenilworth Road back in August, with Craig Mackail-Smith’s penalty earlier cancelling out Gareth Evans’ opener.
And the Hatters have lost on their last six visits to Fratton Park – a run stretches all the way back to 1987.
Adam Webster will miss the game after being sent off at Leyton Orient, leaving Pompey with just one fully-fit centre-back.
Christian Burgess (ankle) and Paul Jones (knee surgery) are both out, while the game will likely arrive too soon for Matt Tubbs (ankle) and Jack Whatmough (knee).
Blues academy graduate Luke Wilkinson could miss out for the visitors with a hamstring problem.
HEAD TO HEAD
Pompey: 14 Wins
Luton: 21 Wins
At Fratton Park
Pompey: 11 Wins
Luton: 4 Wins
Luton 1 (Mackail-Smith)
Pompey 2 (Evans, Tubbs)
August 29 2015
Pompey PlayerHD subscribers can listen to live online commentary from Fratton Park from 2.30pm on Monday.
There will be post-match reaction on the website, Pompey PlayerHD and our official YouTube channel, with extended highlights to follow on Tuesday.
Local listeners can hear commentary on Express FM or BBC Radio Solent (not online), while The News will also have extensive coverage.
There are only a few Family Section tickets remaining for the game. These are not available online and fans must be accompanied by a junior.
Pompey are 3/4 favourites with Sky Bet to claim all three points at Fratton Park, while the visitors can be backed at 19/5.
Click here to read our betting preview and remember to register at www.skybet.com/pompey to earn money for the club whenever you have a flutter.
ALSO IN LEAGUE TWO
Bristol Rovers v Leyton Orient
Cambridge v Barnet
Exeter v AFC Wimbledon
Mansfield v York
Newport v Plymouth
Northampton v Accrington
Notts County v Morecambe
Stevenage v Dag & Red
Wycombe v Crawley
Yeovil v Oxford