O'Brien handed Blues debutPompey ring the changes for tonight's Checkatrade Trophy clash with Yeovil at Huish Park.
Paul Cook has switched the entire starting XI for the group stage fixture.
Liam O'Brien makes his debut between the sticks, while there is a first appearance for Matt Clarke since he joined the Blues on a permanent basis.
Pompey: O'Brien; Close, Barton, Clarke, Naismith; May, Linganzi; Tollitt, Bennett (c), Evans; Smith
Subs: Hall, T.Davies, Chaplin, Hunt