Freeman, Burgess and Roberts all come in
Michael Smith makes his Fratton debut against Bristol Rovers this afternoon.
Paul Cook has made three changes from the side that drew at Morecambe during the week.
Kieron Freeman is handed a debut at right-back, while there are also starts for Christian Burgess and Gary Roberts.
Ben Davies, Adam Webster and Gareth Evans all drop to the bench.
Pompey: Fulton; Freeman, Burgess, Clarke, Stevens; Close, Doyle (c); Roberts, McNulty, Bennett; Smith
Subs: Bass, Davies, Webster, Barton, Evans, McGurk, Chaplin