A look at Pompey's 2016/17 opponents
It was a case of so near, yet so far for Accrington last season, as failure to beat Stevenage on the final day saw them miss out on automatic promotion.
They then suffered an extra-time defeat to AFC Wimbledon – who grabbed the final spot in League One – in the play-offs.
Manager: John Coleman
Ground: Crown Ground
Distance from Fratton Park: 275.1 miles
Estimated drive time: 4 hours 29 minutes
2015/16 position: 4th in League Two
2016/17 title odds: 28/1
Pompey v Accrington last season: D 0-0 (H), W 3-1 (A)
It was a comfortable first season back in the Football League for Barnet, who secured a mid-table finish.
They are led by former Pompey midfielder Martin Allen, who made 46 appearances during his time at Fratton Park in 1990s.
Manager: Martin Allen
Ground: The Hive
Distance from Fratton Park: 84.9 miles
Estimated drive time: 1 hour 47 minutes
2015/16 position: 15th in League Two
2016/17 title odds: 50/1
Pompey v Barnet last season: W 3-1 (H), L 0-1 (A)
Pompey fans can empathise with the fate of their Blackpool counterparts, who saw their side relegated to the fourth tier last term having played Premier League football as recently as 2011.
That led to the departure of Neil McDonald as manager, with Gary Bowyer becoming their eighth boss in the past four years.
Manager: Gary Bowyer
Ground: Bloomfield Road
Distance from Fratton Park: 283.2 miles
Estimated drive time: 4 hours 35 minutes
2015/16 position: 22nd in League One
2016/17 title odds: 12/1
Pompey v Blackpool last season: N/A
Cambridge were unable to break into the play-offs last season, despite ending the campaign with an eight-match unbeaten run.
Pompey have won their past five meetings with United and netted nine times on their two most recent visits to the Abbey Stadium.
Manager: Shaun Derry
Ground: Abbey Stadium
Nickname: The Us
Distance from Fratton Park: 137.6 miles
Estimated drive time: 2 hours 41 minutes
2015/16 position: 9th in League Two
2016/17 title odds: 14/1
Pompey v Cambridge last season: W 3-1 (A), W 2-1 (H)
A play-off berth looked on the cards for the Cumbrians at one stage of the season before they eventually had to settle for 10th spot.
But that is still some achievement when you consider that terrible flooding in December meant they had to play ‘home’ games at Preston, Blackburn and Blackpool.
Manager: Keith Curle
Ground: Brunton Park
Distance from Fratton Park: 351.5 miles
Estimated drive time: 5 hours 35 minutes
2015/16 position: 10th in League Two
2016/17 title odds: 20/1
Pompey v Carlisle last season: D 2-2 (A), W 1-0 (H)
Cheltenham regained Football League status at the first attempt after romping to the National League title last term.
They lost just once at home all season and finished with 101 points – 12 clear of nearest challengers Forest Green.
Manager: Gary Johnson
Ground: Whaddon Road
Distance from Fratton Park: 114.9 miles
Estimated drive time: 2 hours 6 minutes
2015/16 position: 1st in National League
2016/17 title odds: 25/1
Pompey v Cheltenham last season: N/A