A look at Pompey's 2016/17 opponents
Pools fans will have enjoyed a comfortable mid-table finish last term after seeing their side finish just one place above the relegation zone in 2014/15 season.
Pompey did the double over the north-east outfit – hitting six goals past them without reply – and are unbeaten in the last seven meetings between the sides.
Manager: Craig Hignett
Ground: Victoria Park
Distance from Fratton Park: 330 miles
Estimated drive time: 5 hours 22 minutes
2015/16 position: 16th in League Two
2016/17 title odds: 50/1
Pompey v Hartlepool last season: W 4-0 (H), W 2-0 (A)
Andy Hessenthaler was appointed permanent boss at the start of June, having guided the team for the final five games of last season.
He becomes the seventh different man to take charge of Orient since Francesco Becchetti bought the club in the summer of 2014.
Manager: Andy Hessenthaler
Ground: Brisbane Road
Distance from Fratton Park: 108.6 miles
Estimated drive time: 2 hours 3 minutes
2015/16 position: 8th in League Two
2016/17 title odds: 10/1
Pompey v Leyton Orient last season: L 2-3 (A), L 0-1 (H)
Nathan Jones has worked quickly to strengthen his squad after they missed out on the play-offs last season.
He has brought in striker Danny Hylton and defender Johnny Mullins after the duo helped Oxford win automatic promotion last term.
Manager: Nathan Jones
Ground: Kenilworth Road
Distance from Fratton Park: 96.9 miles
Estimated drive time: 1 hour 45 minutes
2015/16 position: 11th in League Two
2016/17 title odds: 9/1
Pompey v Luton last season: W 2-1 (A), D 0-0 (H)
Mansfield have been extremely busy in the transfer marker after their mid-table finish in League Two last term.
Boss Adam Murray has already brought in defenders Rhys Bennett and George Taft, wingers CJ Hamilton and Ashley Hemmings, and striker Danny Rose.
Manager: Adam Murray
Ground: Field Mill
Distance from Fratton Park: 208.6 miles
Estimated drive time: 3 hours 33 minutes
2015/16 position: 12th in League Two
2016/17 title odds: 25/1
Pompey v Mansfield last season: D 0-0 (H), D 1-1 (A)
The thought of a trip to Morecame will still send a shiver down the spine of Pompey fans following goalkeeper Barry Roche’s last-gasp leveller at the Globe Arena back in February.
League Two sponsors Sky Bet believe the Shrimps are the side least likely to win the fourth tier title, pricing them at 80/1.
Manager: Jim Bentley
Ground: Globe Arena
Distance from Fratton Park: 292.4 miles
Estimated drive time: 4 hours 50 minutes
2015/16 position: 21st in League Two
2016/17 title odds: 80/1
Pompey v Morecambe last season: D 3-3 (H), D 1-1 (A)
Newport appeared to be certainties for relegation last term after winning just one of their opening 13 games.
But they improved once John Sheridan replaced Terry Butcher as manager, eventually finishing nine points clear of the drop zone.
Manager: Warren Feeney
Ground: Rodney Parade
Distance from Fratton Park: 142.3 miles
Estimated drive time: 2 hours 23 minutes
2015/16 position: 22nd in League Two
2016/17 title odds: 50/1
Pompey v Newport last season: W 1-0 (A), L 0-3 (H)