All you need to know about League Two clash
It is a return to league action for Pompey on Saturday (3pm kick-off) when they travel to Leyton Orient.
Paul Cook’s troops will be facing a side who have recently changed their manager following a slow start to the campaign.
Andy Hessenthaler was sacked after just five months in charge, despite signing a new deal over the summer.
His replacement is 60-year-old Alberto Cavasin, who can count Fiorentina, Brescia and Sampdoria among his former clubs.
The Italian becomes the eighth man to be appointed manager since Francesco Becchetti bought the club in 2014.
Orient have only won three league games so far this season – and just once on their own patch.
They have failed to be victorious in any of their previous five outings, a run that has seen them slip down to 18th in the fourth tier table.
The Londoners did the double over Pompey last term, though, triumphing 1-0 at Fratton Park in February following a 3-2 Boxing Day win in the capital.
Adam Buxton (ankle) and Drew Talbot (hamstring) are both out for Pompey, while Noel Hunt (groin) is also a doubt.
Former Pompey players Nigel Atangana and Paul McCallum could feature for the hosts, who are without the suspended Robbie Weir.
Read what Paul Cook and Kal Naismith have to say about the game or watch pre-match video content on Pompey PlayerHD.
HEAD TO HEAD
Pompey: 15 Wins
Leyton Orient: 13 Wins
At Leyton Orient
Pompey: 5 Wins
Leyton Orient: 8 Wins
Pompey have sold their entire allocation of tickets and no more will be made available.
Pompey PlayerHD subscribers can listen to live commentary from the Matchroom Stadium from 2pm on Saturday.
There will be post-match reaction on the website, Pompey PlayerHD and our official YouTube channel, with highlights to follow on Sunday.
Local listeners can hear commentary on Express FM or BBC Radio Solent, while The News will also have extensive coverage.
Pompey are 21/20 favourites with Sky Bet to claim all three points, while the hosts can be backed at 13/5.
Click here to read our full betting preview and sign-up to www.skybet.com/pompey for great offers.
ALSO IN LEAGUE TWO
Mansfield v Notts County (12.15pm)
Accrington v Cheltenham
Blackpool v Cambridge
Colchester v Newport
Doncaster v Barnet
Exeter v Grimsby
Hartlepool v Crawley
Luton v Crewe
Morecambe v Carlisle
Stevenage v Plymouth
Yeovil v Wycombe