Pompey will look to secure victory in front of the nation when they travel to Gillingham for a televised fixture on Sunday.
And Kenny Jackett’s side are 10/11 favourites with Sky Bet to continue their up-and-down start to the League One campaign by securing all three points.
The hosts – who are only being kept off the foot of the table by Plymouth – can be backed at 3/1, with the draw at 5/2.
Pompey triumphed 1-0 when the sides last met for a league contest in 2003 and a repeat of that scenario is available at 6/1, with a 2-1 victory at 15/2.
Jamal Lowe has enjoyed a bright start to the season and there are odds of 9/2 on him adding to his tally in a Blues win.
You can also take a punt on the winger to net from outside the area at 14/1 or to score and be carded at 28/1.
With Brett Pitman and Conor Chaplin both sidelined, Oliver Hawkins – who was used as a makeshift defender earlier in the week – is the 5/1 favourite to bag the opener.
Elsewhere in the first goalscorer market, Kal Naismith Matty Kennedy and Stuart O’Keefe are on offer at 6/1, 15/2 and 25/1 respectively.
Please gamble responsibly and remember that odds are subject to change.
Sign-up to a Sky Bet account now at www.skybet.com/pompey for more odds and some great offers.