Pompey will look to build on an opening day triumph when they travel to Blackpool this weekend.
And Kenny Jackett’s side are the 7/5 favourites with Sky Bet to collect a maximum haul of points at Bloomfield Road.
The hosts – who saw Gary Bowyer step down as manager earlier in the week – can be backed at 2/1, with the draw at 9/4.
Pompey emerged 3-2 victors in the corresponding fixture last season and a repeat of that scenario carries odds of 40/1.
Perhaps more likely, however, would be a 1-0 win at 11/2 or the choice of a 2-0 or 2-1 success at 9/1.
You can also take advantage of a Sky Bet boost, with the visitors coming out on top and both teams scoring moving from 9/2 to 11/2.
The half-time/full-time market has the Blues recovering from an interval triumph before eventually emerging with all the points at 33/1.
And if you think that Craig MacGillivray will keep a second successive clean sheet, then that is on offer at 13/8.
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