The road to Wembley was ended – at least in the Carabao Cup – by AFC Wimbledon during the week.
But the Blues will look to put that behind them and continue their encouraging start to the 2018/19 League One campaign.
Kenny Jackett’s side will try to make it three successive victories by seeing off Oxford at Fratton Park this weekend.
It has been the reverse for their opponents, who recovered from back-to-back league defeats to beat Coventry in the cup.
Those losses against Barnsley (0-4) and Fleetwood (0-2) mean they currently prop up the division, albeit at a very early stage.
United are looking to improve on last season’s 16th-placed finish, with just a six-point buffer between them and the drop zone.
Karl Robinson has taken advantage of his first pre-season at the helm by making a host of signings, including the loan capture of ex-Pompey winger Ricky Holmes.
His maiden game as head coach was at Fratton Park back in March and it ended in defeat, courtesy of Kal Naismith’s goal and a Brett Pitman brace.
TEAM NEWS
Pompey are still without the injured pair of Dion Donohue (groin) and Nathan Thompson (knee), but new loan midfielder Ben Thompson could make his debut.
Former Blues keeper Simon Eastwood (finger) and Samir Carruthers (knee) miss out for the visitors, while Holmes (back) is also a doubt.
VIEW FROM THE DRESSING ROOM
Read the thoughts of Kenny Jackett and Matt Clarke and register for a free iFollow account to watch the below videos.
HEAD TO HEAD
Overall
Pompey: 24 wins
Oxford: 21 wins
17 draws
At Fratton Park
Pompey: 16 wins
Oxford: 4 wins
9 draws
TICKETS
Seats can be secured online here or from the ticket office in Anson Road.
Subject to availability, they will be sold from both ticket offices from 9am on Saturday, while collections can be made from main reception.
MATCH COVERAGE
Domestic iFollow subscribers can listen to live commentary from Andy Moon and Guy Whittingham by signing into their account and visiting the match centre from 2pm on Saturday.
Overseas subscribers and match pass holders can watch the action – now with on-screen graphics – and commentary will begin from around 10 minutes before kick-off.
Click here for more information about using iFollow on a matchday and click here for information on downloading the app, so you can access content on your mobile device.
We will have updates throughout the game on Twitter and the match centre. You can also see behind-the-scenes content on our Instagram story and Snapchat account.
There will be post-match reaction on the website, iFollow and our official YouTube channel, with highlights to follow on Sunday.
Local listeners can hear commentary by tuning in to either Express FM or BBC Radio Solent.
BETTING
Pompey are the 17/20 favourites with Sky Bet to secure all three points, while the visitors can be backed at 10/3.
Click here to read our full betting guide and visit www.skybet.com/pompey to earn money for the club when you place a bet. Please gamble responsibly.
ALSO IN LEAGUE ONE
Accrington v Charlton
Barnsley v AFC Wimbledon
Burton v Doncaster
Coventry v Plymouth
Fleetwood v Rochdale
Peterborough v Luton
Shrewsbury v Blackpool
Southend v Bradford
Walsall v Gillingham
Wycombe v Bristol Rovers
Sunday
Sunderland v Scunthorpe
LAST MEETING