Pompey will look to build on successive victories when they make an Easter visit to Walsall on Saturday.
Kenny Jackett’s side have beaten Oldham and Oxford to improve their chances of snatching a play-off place.
Now they face a Saddlers side who are more concerned with events at the opposite end of the League One table.
A home defeat to Wigan meant they sat just four points above the drop zone going into the bank holiday weekend.
It was their third successive loss and a fifth from the past six games – a run of form that led to the dismissal of Jon Whitney as manager.
Dean Keates was appointed from Wrexham to replace him and will be in the dug-out for the first time on Saturday after watching the Latics reverse from the stands.
It was a 1-1 draw when the sides met at Fratton Park earlier in the season, with Luke Leahy’s opener cancelled out by a Brett Pitman penalty.
The Blues were beaten on their most recent visit to the Bescot Stadium in January 2013, although goals from Kevin Harper and Svetoslav Todorov secured a win en route to promotion 10 years earlier.
Oli Hawkins and Stuart O’Keefe are available for Pompey again after recovering from hamstring and groin injuries respectively.
But the Blues are still without goalkeeper Stephen Henderson (thigh) and midfielder Danny Rose (leg).
On-loan Walsall defender Krystian Bielik has returned to Arsenal with a hamstring problem, while Joe Edwards (knee) also missed out.
HEAD TO HEAD
Pompey: 10 wins
Walsall: 7 wins
Pompey: 3 wins
Walsall: 4 wins
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ALSO IN LEAGUE ONE
Bradford v Walsall
Charlton v Rotherham
Doncaster v AFC Wimbledon
Fleetwood v Bristol Rovers
MK Dons v Blackburn
Oldham v Blackpool
Peterborough v Northampton
Scunthorpe v Plymouth
Shrewsbury v Oxford
Southend v Gillingham
Bury v Rochdale (7.45pm)