Recent games have seen Pompey put their league ambitions on hold to focus on progressing in cup competitions.
But the battle for points resumes at Glanford Park on Saturday when Kenny Jackett’s side visit Scunthorpe.
International call-ups saw last week’s clash with Charlton postponed and Sunderland missed the chance to knock the Blues off top spot.
But they know that the only way to guarantee staying there is by securing a first victory on The Iron’s patch since 1963.
It has not been a happy hunting ground for Pompey in recent years, with a 5-1 hammering in 2014 their biggest low.
Lee Novak and Duane Holmes were on target to secure a comfortable win for the hosts in last season’s meeting.
Scunthorpe have reached the third tier play-offs in each of the past two campaigns, but are finding life a bit trickier this time around.
Stuart McCall’s men are currently in 17th spot and recently suffered five successive league defeats, although did beat Bristol Rovers in their last outing.
Brett Pitman has recovered from a minor knee problem, but Pompey are still without Dion Donohue (hamstring) and Joe Mason (groin).
Ryan Coloclough is a long-term absentee for Scunthorpe, while the hosts are also missing Jordan Clarke (shoulder), Matt Gilks (knee), Josh Morris (jaw), Levi Sutton (thigh) and Rory Watson (arm).
HEAD TO HEAD
Pompey: 8 wins
Scunthorpe: 9 wins
Pompey: 2 wins
Scunthorpe: 6 wins
Seats can be secured from Pompey until 4pm on Friday or bought from the cash turnstiles at Scunthorpe on the day of the game. Click here for more information.
Overseas subscribers and match pass holders can watch the action – now with on-screen graphics – and commentary will begin from around 10 minutes before kick-off.
ALSO IN LEAGUE ONE
Coventry v Peterborough (7.45pm)
AFC Wimbledon v Southend
Barnsley v Doncaster
Blackpool v Burton
Bradford v Oxford
Charlton v Bristol Rovers
Gillingham v Luton
Plymouth v Fleetwood
Rochdale v Accrington
Walsall v Sunderland
Wycombe v Shrewsbury