Pompey will aim to extend their winning run in the league to five matches when they host Rochdale this weekend.
And Kenny Jackett’s side are the 4/7 favourites with Sky Bet to secure all three points at Fratton Park.
The visitors – who sit just outside the relegation places – can be backed at 17/4, with the draw at 29/10.
Pompey won 3-1 in the reverse fixture back in September and a repeat of that scenario carries odds of 12/1.
Punters might instead be tempted by a narrower 1-0 victory at 6/1 or even a barnstorming 4-0 triumph at 22/1.
You can also take advantage of a Sky Bet boost, with the Blues coming out on top in a contest where both sides find the target moving from 9/4 to 11/4.
There is the option to back both sides hitting the net at 4/5, doing that in each half at 10/1 or Pompey winning without conceding at 13/8.
Omar Bogle, Ronan Curtis and Jamal Lowe are the joint 7/2 favourites to net the opener, ahead of Oli Hawkins and Brett Pitman at 9/2.
Elsewhere in the first goalscorer market, Gareth Evans, Ben Close and Christian Burgess are available at 13/2, 12/1 and 50/1 respectively.
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