Pompey will look to revive their stuttering league form when they make the trip to Plymouth on Saturday.
Kenny Jackett’s side began 2019 with victory over AFC Wimbledon, but since then their only wins have arrived in cup competitions.
They still sit just one point outside the automatic promotion places, however, and will face a team in 16th position in Devon.
But it has been an incredible rise for an Argyle side who were without a League One triumph until the 12th game of the season.
The Pilgrims were in the drop zone at the start of the year, but have won five of their past six games to move four points clear.
It means that Derek Adams’ men sit at the top of the division’s form table as they look to keep climbing the standings.
There are echoes of last term, when it also appeared that Plymouth would be embroiled in a battle against relegation, only to end up narrowly missing out on a play-off spot.
Ronan Curtis’ brace and a goal from Jamal Lowe saw Pompey ease to a 3-0 victory when the sides met earlier in the campaign.
Their two most recent Home Park clashes have ended all square, with the Blues last winning there in August 2015.
Pompey will be without Luke McGee (wrist) and Jack Whatmough (knee), while Tom Naylor starts a two-match ban.
There are also doubts over the fitness of Dion Donohue (shin), Lloyd Isgrove (knee) and Bryn Morris (ankle).
Conor Grant (calf), Joel Grant (thigh) and Jamie Ness (calf) are all missing for Plymouth, who could hand a debut to defender Lloyd Jones.
HEAD TO HEAD
Pompey: 28 wins
Plymouth: 24 wins
At Home Park
Pompey: 10 wins
Plymouth: 14 wins
Pompey have sold their full allocation of tickets and no more will be available at the ground on Saturday.
Overseas subscribers and match pass holders can watch the action – now with on-screen graphics – and commentary will begin from around 10 minutes before kick-off.
ALSO IN LEAGUE ONE
AFC Wimbledon v Burton
Blackpool v Walsall
Bradford v Fleetwood
Bristol Rovers v Shrewsbury
Charlton v Southend
Doncaster v Peterborough
Gillingham v Barnsley
Luton v Wycombe
Oxford v Sunderland
Rochdale v Coventry
Scunthorpe v Accrington