Pompey secured a narrow victory over Southampton Saints to book their place in the final of the Hampshire Cup.
Danielle Rowe netted the only goal of the game during the first half at the PMC Stadium, as the Blues seek to lift the trophy for an 11th successive season.
And having also seen off Southampton FC in the last round, they now face Southampton Women in another derby clash.
Pompey made a bright start to their last four contest, with Emily Paines called into action to save efforts from Shannon Albuery and Rowe.
Albuery then sent another shot past the post following some neat build-up play between Jade Bradley and Katie James.
And when Emma-Jane May laid the ball off for Carla Perkins on the edge of the box, the midfielder fired narrowly wide.
But the deadlock was broken on 18 minutes, as ROWE controlled a cross from Rebekah Tonks before calmly slotting home.
Pompey kept pushing, though, and James saw her attempt fly agonisingly off target after cutting inside from the left.
There had not been too many concerns at the other end, although Alisha Buckingham want close with a curling effort when James’ pass was intercepted.
Most of the action was taking place in the Southampton half and Perkins, Albuery and Rowe all went close before the break.
Half Time: Pompey 1 Southampton 0
It was a similar story when the action restarted and Albuery was inches away from meeting a delivery from Bradley.
Bradley then had a chance of her own that cleared the crossbar, while Albuery then curled a shot just past the post.
A free-kick from Perkins went over and Paines did well to stop Rachel Panting’s low ball across goal from reaching Albuery.
Southampton were being forced to defend deep and a dangerous James cross was punched behind by Paines, who then kept out a powerful strike from the midfielder.
The hosts were showcasing some neat passing football, with one move ending with Albuery rounding the keeper and rolling the ball against the post.
Albuery and Ellie Kirby also went close in the final few minutes, as Pompey had to settle for just a one-goal triumph as they reached the final yet again.
"We’ve had our name on the cup on several occasions and we all want to retain it."
Blues boss Jay Sadler said: “We’ve been professional throughout our games in the competition and scored some superb goals.
“There wasn’t the level of sharpness or intensity that I expect, but we’ve got to be happy that we’re in the final.
“We’ve had our name on the cup on several occasions and we all want to retain it, but when we do get good opportunities, we have to finish them off.”
Pompey: Rowlands; Tonks (Kirby 86), Younger, Southgate (c), May (A.Collighan 63); Rowe, Perkins; Panting (Eadon 83), Bradley, James; Albuery
Sub not used: Currie