Pompey will try to reclaim top spot in League One when they travel to current leaders Luton on Tuesday evening.
But it is the hosts who are the 11/8 favourites with Sky Bet to collect all three points at Kenilworth Road.
The Blues triumphed 1-0 when the sides met at Fratton Park on the opening day of the season and a repeat of that scenario carries odds of 8/1.
Or you could hedge your bets by picking them to achieve success by either a 1-0, 2-0 or 2-1 scoreline at 11/4.
In the Request A Bet specials, the match containing over 4.5 goals, 15+ corners and 70+ booking points is on offer at 250/1.
Perhaps more realistic is both sides finding the target and securing at least three corners each at 11/8.
Please gamble responsibly and remember that all odds are subject to change. When the fun stops, stop.
Visit Sky Bet for more great offers and promotions and use this link when you bet to also earn money for Pompey.