Pompey will look for a return to winning ways when they make the relatively short trip to Oxford on Saturday.
And Kenny Jackett’s side are the 13/10 favourites with Sky Bet to secure all three points at the Kassam Stadium.
The hosts – who are currently residing in the League One relegation zone – can be backed at 21/10, with the draw also at 21/10.
Pompey eased to a 4-1 triumph when the sides met on the south coast earlier in the campaign and a repeat of that scenario is priced at 50/1.
More conservative punters might instead prefer to put their money on a 1-0 win at 6/1 or 2-1 success at 9/1.
You can also take advantage of a Sky Bet boost, with the Blues coming out on top in a contest where both teams hit the target moving from 4/1 to 5/1.
Fancy predicting the margin of victory? Take a look by the visitors winning by one goal at 3/1, two at 13/2 or at least three at 12/1.
And take a look at Pompey recovering from an interval deficit to collect a maximum haul at a tempting 33/1.
Jamal Lowe is the 11/2 favourite to net the opener this weekend, ahead of Ronan Curtis and Brett Pitman at 6/1.
Elsewhere in the first goalscorer market, Gareth Evans, Andy Cannon and Jack Whatmough are available at 10/1, 18/1 and 50/1 respectively.
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