Pompey will look to secure third spot in the table when they host Accrington in the final game of the regular season on Saturday.
And Kenny Jackett’s side are the 2/5 favourites with Sky Bet to collect all three points at Fratton Park.
The visitors – who ensured survival by thrashing Plymouth last week – can be backed at 6/1, with the draw at 7/2.
It finished 1-1 when the sides met up north earlier in the campaign and a repeat of that scenario carries odds of 15/2.
More optimistic punters might prefer to put their money on a 2-0 triumph at 11/1 or even a 4-1 success at 20/1.
You can also take advantage of a Sky Bet boost, with the Blues coming out on top in a contest where both sides find the target moving from 2/1 to 5/2.
The hosts are listed as evens to find the net in each half or keep a clean sheet and 4/11 to be first to take the lead.
Those expecting a comfortable afternoon should take a look at 4/1 for Pompey scoring in the first 10 minutes or 5/2 for grabbing two goals before the break.
Omar Bogle, Ronan Curtis and Jamal Lowe are the joint 10/3 favourites to net the opener, ahead of Oli Hawkins and Brett Pitman at 4/1.
Elsewhere in the first goalscorer market, Viv Solomon-Otabor, Ben Close and Christian Burgess are available at 13/2, 12/1 and 50/1 respectively.
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