The next side to put Pompey’s unbeaten home league record to the test is struggling Southend on Tuesday evening.
But Kenny Jackett’s side are the 3/10 favourites with Sky Bet to secure all three points at Fratton Park.
The visitors – who have recorded just one league victory so far this season – can be backed at 8/1, with the draw at 4/1.
Pompey triumphed 2-0 when the sides met on the south coast last season and a repeat of that scoreline carries odds of 5/1.
Punters might, however, be tempted to put their money on a narrower 1-0 success at 13/2 or even a 4-0 win at 12/1.
You can also take advantage of a Sky Bet boost, with the Blues coming out on top in a contest where both sides find the target moving from 15/8 to 9/4.
Those anticipating an action-packed start to the contest can take a look at Pompey and the Shrimpers both scoring in the first half at 9/2.
Or if you think Jackett’s men will have to battle from behind before claiming the points, then that is on offer at 9/1.
Leading marksman Ellis Harrison and fellow forward John Marquis are the joint 7/2 favourites to net the opener.
Elsewhere in the first goalscorer market, Gareth Evans, Ben Close and Christian Burgess are available at 11/2, 6/1 and 50/1 respectively.
Please gamble responsibly and remember that all odds are subject to change. When the fun stops, stop.
Visit Sky Bet for more great offers and promotions and use this link when you bet to also earn money for Pompey.
Please note that in-stadia betting is no longer available at Fratton Park.