Pompey will look to make it three League One wins in succession when they host Gillingham on Saturday.
And Kenny Jackett’s side are the 7/10 favourites with Sky Bet to secure all three points at Fratton Park.
The visitors – who are sitting one point higher in the table – can be backed at 18/5, with the draw at 13/5.
Pompey were beaten 2-0 in last season’s corresponding fixture and there are odds of 7/1 on them gaining revenge by that scoreline.
Punter might instead prefer to put their money on a narrower 1-0 success at 13/2 or a comfortable 4-0 triumph at 28/1.
And you can also take advantage of a Sky Bet boost, with the Blues coming out on top in a contest where both teams find the target moving from 9/4 to 11/4.
Those expecting an afternoon free of tension might want to take a look at the hosts winning each half at 6/4.
Or if you think they will have to work hard to claim the points, then recovering from an interval deficit to emerge victorious is 25/1.
John Marquis is the 16/5 favourite to net the opener, ahead of fellow forward – and leading marksman – Ellis Harrison at 4/1.
Elsewhere in the first goalscorer market, Brett Pitman, Gareth Evans and Sean Raggett are available at 9/2, 11/2 and 16/1 respectively.
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Please note that in-stadia betting is no longer available at Fratton Park.