Pompey complete their group stage fixtures in the Leasing.com Trophy with a trip to Oxford on Tuesday evening.
The hosts – who are currently sitting ninth in the League One standings – are the 13/10 favourites with Sky Bet to secure all three points.
Kenny Jackett’s side can be backed at 9/5 to claim a maximum haul at the Kassam Stadium, with the draw at 9/4.
The Blues were beaten 2-1 on their last visit to United’s ground and a repeat of that scenario carries odds of 7/1.
More optimistic punters, however, might prefer to put their money on a 1-0 win for the visitors at 17/2 or 2-0 at 12/1.
There is also the option to hedge your bets by selecting either a 1-0, 2-0 or 2-1 Pompey success at 3/1.
Alex Bass is likely to be between the sticks for the Blues and if you fancy him to keep a clean sheet then that is on offer at 12/5.
John Marquis is the 9/2 favourite to net the opener, ahead of fellow forwards Ellis Harrison at 11/2 and Brett Pitman at 13/2.
But Jackett is likely to rotate with a place in the knockout stages already confirmed, so perhaps go for Ryan Williams, Andy Cannon or Paul Downing at 8/1, 25/1 and 50/1 respectively.
Pompey are, of course, the current competition holders and are the 7/1 favourites to retain the trophy at Wembley.
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