Pompey will look to maintain their unbeaten home record in League One when they face Oxford on Saturday.
And Kenny Jackett’s side are the 7/5 favourites with Sky Bet to secure all three points at Fratton Park.
The visitors – who are unbeaten in 11 games in all competitions – can be backed at 9/5, with the draw at 23/10.
Pompey eased to a 4-1 success in last season’s corresponding fixture and a repeat of that scoreline carries odds of 50/1.
More conservative punters might instead prefer to put their money on a 1-0 win at 15/2 or a 2-0 triumph at 11/1.
And you can also take advantage of a Sky Bet boost, with the Blues coming out on top in a contest where both sides hit the target moving from 7/2 to 9/2.
Then there is the opportunity to back Craig MacGillivray to keep a clean sheet in a home victory at 7/2.
Or you might fancy the hosts to recover from an interval deficit before snatching a maximum haul at 28/1.
John Marquis is the 9/2 favourite to net the opener, ahead of fellow forward and leading marksman Ellis Harrison at 5/1.
Elsewhere in the first goalscorer market, Gareth Evans, Ryan Williams and Lee Brown are available at 8/1, 17/2 and 66/1 respectively.
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Please note that in-stadia betting is no longer available at Fratton Park.