Pompey postponed last month’s scheduled fixture against Southend after three players were selected to represent their country.
They have made the decision to go ahead with Saturday’s clash with Gillingham, however, which coincides with another international break.
Regular keeper Craig MacGillivray and fellow Scot Ross McCrorie are both missing, although Ronan Curtis can feature after withdrawing from the Republic of Ireland squad.
But there have already been three blank weekends this season, courtesy of Victorious Festival and Bury’s EFL expulsion.
And with Pompey having won their past two league matches, Kenny Jackett was eager to avoid another break.
The Blues boss said: “I think it’s the right decision because we’ve had some big gaps between games at times this season.
“That builds up pressure and I didn’t want that to be the case – I think we can get going during October and November, but we need the fixtures for that.
"We want to get into a flow if we can and produce a performance of industry and quality for our supporters."
“I have confidence in Alex Bass and you have to put young players in at some stage. You need to play them when the situation is right.
“I’ve been with him here for a couple of years and, like with all my players, I talk to him on a regular basis.
“We want to get into a flow if we can and produce a performance of industry and quality for our supporters.”
Pompey go into the contest on the back of consecutive League One successes against Bolton and Doncaster.
Jackett said: “Momentum is a big thing – that’s true of all football and not just at Pompey – and Saturday is a big game for us.
“It’s one we’re all excited about but we won’t underestimate the opposition because you have to work hard for every point.
“We’ll certainly have to be at our best on Saturday and it’s an opportunity to keep taking our season forward.
“You look at the team you’re facing, but ultimately judge yourself by your own standards and how your side is progressing.”