Pompey turn their attention to the Carabao Cup on Tuesday, with a mouth-watering south coast derby against Southampton.
It is the Premier League outfit – who were beaten by Bournemouth on Friday night – who are the 1/2 favourites to progress.
Kenny Jackett’s side can be backed at 6/4 to knock out their neighbours at Fratton Park and reach the fourth round.
It finished 2-2 when the sides last met all the way back in 2012 and a repeat of that scoreline after 90 minutes carries odds of 12/1.
More optimistic punters, however, might be tempted to choose a 1-0 victory at 12/1 or 2-0 triumph at 22/1.
Reckon that regulation time will not be able to settle the teams? Either of them winning on penalties is available at 11/2.
Pompey fought from behind to get something from each of the last two derbies, so you could take a look at them recovering from an interval deficit to win at 40/1.
John Marquis is the 5/1 favourite to net the opener, with fellow forward Brett Pitman and Ronan Curtis at 8/1.
Elsewhere in the first goalscorer market, Gareth Evans, Ben Close and Christian Burgess are on offer at 9/1, 12/1 and 80/1 respectively.
And those fans who are dreaming of Wembley should check out the odds of 200/1 on Pompey winning the Carabao Cup.
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Please note that in-stadium betting is no longer available at Fratton Park.