It has been more than seven years since the last chapter of the south coast derby was written.
And Kenny Jackett is looking forward to the next contest between Pompey and their neighbours from across the M27.
Southampton are visiting a sold out Fratton Park for a Carabao Cup third round tie that will be broadcast to the nation and around the world.
Birmingham and QPR have already been accounted for in the competition and Jackett hopes Pompey can take another scalp on Tuesday evening.
The Blues boss said: “We’ve beaten two Championship sides to get through to this round and now we’ve got a big tie against a Premier League club.
“There’s obviously the added incentive of it being a local derby and that should only enhance what is already a very good atmosphere.
“This fixture hasn’t been contested for a number of years and that should add another edge to proceedings.
"There are many derbies that are played all around the country and Portsmouth v Southampton is right up there among the best."
“There is obviously a line that shouldn’t be crossed and I’m sure all of the supporters are aware of that.
“But it’s a definite advantage for us to be at home and we have to make sure that we give a good account of ourselves.
“There are many derbies that are played all around the country and Portsmouth v Southampton is right up there among the best. It’s got a big reputation.”
Pompey go into the game looking for a boost following a disappointing start to the League One campaign.
Jackett said: “We want to be finding some form because we haven’t really done ourselves justice so far this season.
“I think we’ve been in every game and had chances, but one win out of seven in the league isn’t where we want to be.
“So we want to keep improving our performances and this game can be a catalyst, although we can’t wait for things to turn – we have to make it happen.”