Becki Bath bagged a hat-trick as Pompey Women routed Plymouth to ensure a welcome start to life at Westleigh Park.
Jade Widdows and Danielle Rowe also netted two goals each, as the Blues produced a dominant National League display.
Jay Sadler made two changes from the side that beat Moneyfields to lift the PDFA Cup earlier in the week.
Rosie McDonnell and Katie James both returned to the starting line-up, with Kat Cunningham and Tamsin de Bunsen making way.
Pompey started the contest brightly and there were just six minutes on the clock when they broke the deadlock.
McDonnell was able to drive down the left and float a cross into the area, where WIDDOWS was waiting to convert at the back post.
They almost added a quick second, with Katie James beating a defender and drawing a smart save from Poppy Soper.
But it did not take long for the advantage to be doubled, as Rowe stole possession and threaded a pass through for BATH to smash into the net.
And BATH had her second goal of the afternoon on 33 minutes, nodding home a deep cross from Laura Ingram.
Skipper Jade Bradley then almost marked her 50th Blues appearance in style, with a long-range strike that cannoned off the crossbar.
Jazmin Younger was next to go close, courtesy of a header from James’ delivery that Soper managed to tip onto the post.
But the hosts did strengthen their lead on the stroke of the interval, when ROWE volleyed in a cross from McDonnell.
Half Time: Pompey 4 Plymouth 0
The pressure was maintained once the action resumed and Soper was again called into action to stop James converting Widdows’ pass.
It had mostly been a watching brief for Hannah Haughton, but she did have to be alert to keep out Wensday Wise’s lob just before the hour mark.
Most of the chances were still falling the way of the Blues, however, and Widdows fired narrowly wide before the woodwork denied Bath another goal.
Pompey netted again on 77 minutes, as Younger headed James’ cross against the bar and the ball fell kindly for WIDDOWS to nod into an empty net.
And BATH quickly completed her treble, showcasing some tricky footwork before curling a shot around Soper’s grasp.
It had turned into a damage limitation exercise for Argyle, but they were unable to stop another goal being added at the death.
An effort from substitute Mia Adaway was well saved by Soper, with the ball running free for ROWE to tap home and leave the Blues in seventh heaven.
Pompey: Haughton; Younger, Ingram, Rowe; Bridge, Bradley (c) (Tonks 82), Rowbotham, McDonnell (Adaway 60); Widdows, James, Bath (Mason 82)