Pompey have rung the changes for this evening's EFL Trophy group stage contest at Southend.
Ryan Williams is the only player who started Saturday's League One victory over Burton to keep his place.
Rasmus Nicolaisen makes his Blues debut at the heart of the back-line, with Haji Mnoga, James Bolton, Paul Downing and Cam Pring joining him in defence and Alex Bass between the sticks
Pompey: Bass; Mnoga, Bolton, Nicolaisen, Downing, Pring; Close (c), Cannon; Williams, Marquis, Curtis
Subs: MacGillivray, Johnson, Raggett, Morris, Jacobs, Harness, Harrison