Despite not playing last weekend and losing on Tuesday night, Pompey remain fourth in the League One standings.
But they will be looking for an instant return to winning ways against Blackpool in order to keep pace with the top two.
Their opponents are 14th in the table and eight points adrift of the play-off places, with as many as three games in hand on the sides around them.
Neil Critchley’s men have won three of their past four fixtures – a run that began with a 5-0 rout of Wigan.
That result is one of four victoriess on the road for the Seasiders, who have also collected a maximum haul at Burton, Peterborough and neighbours Fleetwood.
They also caused an FA Cup upset last month by knocking out Premier League side West Brom on penalties at Bloomfield Road, only to exit at the hands of Brighton in the fourth round.
The Covid-19 pandemic meant that there was no south coast meeting between the teams last season.
Blackpool won 1-0 on their most recent visit to Fratton Park in January 2019 and also triumphed by the same scoreline on their own patch a few months ago.
TEAM NEWS
Pompey have no new injury concerns, although Alex Bass (leg) and Michael Jacobs (hamstring) are still sidelined.
Blackpool defender Marvin Ekpiteta will miss out after being sent for a scan on a troublesome hamstring problem.
Keshi Anderson (knee), Daniel Gretarsson (hamstring) and CJ Hamilton (hamstring) are all unable to feature, while Gary Madine (groin) is a doubt.
VIEW FROM THE DRESSING ROOM
Read the thoughts of Joe Gallen and George Byers ahead of the game.
HEAD TO HEAD
Overall
Pompey: 22 wins
Blackpool: 28 wins
23 draws
At Fratton Park
Pompey: 15 wins
Blackpool: 11 wins
10 draws
OFFICIALS
Referee: Sam Allison
Assistants: Justin Amey and Simon Shaw
Fourth Official: Adrian Tranter
MATCH COVERAGE
Supporters in the UK can watch the action live – with graphics, commentary and replays – by purchasing a match pass for £10.
Subscribers will, as usual, be able to listen to listen to live commentary from Andy Moon and Guy Whittingham by signing into their account and visiting the match centre from 2pm.
Please note that subscribers based in the UK and Ireland will still need to purchase a match pass in order to watch the game live.
Click here for more information about using iFollow on a matchday and click here for information on downloading the app, so you can access content on your mobile device.
We will have updates throughout the game on Twitter and the match centre. You can also see behind-the-scenes content on our Instagram story.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
Local listeners can hear commentary by tuning in to either Express FM or BBC Radio Solent.
BETTING
Pompey are the 11/10 favourites with VBET to secure all three points, while the visitors can be backed at 5/2.
Click here to find a comprehensive list of odds for Saturday’s game. Please gamble responsibly.
ALSO IN LEAGUE ONE
Games kick-off at 3pm unless stated
Gillingham v Bristol Rovers (1pm)
Accrington v Shrewsbury
Burton v Sunderland
Doncaster v Hull
Fleetwood v Charlton
Ipswich v Oxford
MK Dons v Northampton
Peterborough v AFC Wimbledon
Rochdale v Plymouth
Swindon v Crewe
Wigan v Lincoln
CLASSIC CONTEST