Pompey Women will begin the 2021/22 campaign with a home match against Plymouth.
Jay Sadler’s side host the Pilgrims in a National League Southern Premier Division contest at Westleigh Park on Sunday, August 15.
They then have successive games on the road at Cardiff and Crawley, with the latter a midweek contest.
The fixtures that most fans will want to know about, however, are the eagerly anticipated south coast derbies.
Southampton are scheduled to visit Westleigh Park on Sunday, October 24, with the return fixture on Sunday, March 6.
The Blues will bring the curtain down on the season with successive home fixtures against Ipswich and MK Dons.
Please note that the dates of all fixtures are subject to change.
| Date | Opposition |
| Sun, Aug 15 | Plymouth (H) |
| Sun, Aug 22 | Cardiff (A) |
| Wed, Aug 25 | Crawley (A) |
| Sun, Aug 29 | Oxford (H) |
| Sun, Sep 5 | Keynsham (H) |
| Sun, Sep 26 | Hounslow (A) |
| Sun, Oct 3 | Gillingham (A) |
| Wed, Oct 6 | Chichester & Selsey (H) |
| Sun, Oct 24 | Southampton (H) |
| Sun, Oct 31 | London Bees (A) |
| Sun, Nov 14 | Bridgwater (H) |
| Sun, Dec 5 | Ipswich (A) |
| Sun, Dec 12 | MK Dons (A) |
| Sun, Jan 16 | Plymouth (A) |
| Sun, Jan 23 | Cardiff (H) |
| Wed, Jan 26 | Crawley (H) |
| Sun, Jan 30 | Oxford (A) |
| Sun, Feb 6 | Keynsham (A) |
| Sun, Feb 13 | Hounslow (H) |
| Sun, Feb 27 | Gillingham (H) |
| Wed, Mar 2 | Chichester & Selsey (A) |
| Sun, Mar 6 | Southampton (A) |
| Sun, Mar 13 | London Bees (H) |
| Sun, Mar 20 | Bridgwater (A) |
| Sun, Apr 10 | Ipswich (H) |
| Sun, Apr 17 | MK Dons (H) |