Pompey withstood a late barrage of Wycombe pressure to claim all three points in their League One contest at Adams Park.
Both sides created chances in an absorbing contest, with Danny Cowley's men receiving a let off when Alex Bass saved Joe Jacobson's poor penalty.
And the only goal arrived in the second half, as George Hirst collected a Ronan Curtis pass and squared for Marcus Harness to bundle home.
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