Cherelle Khassal netted the only goal as Pompey Women beat Milton Keynes Dons in a National League contest at Stadium MK.
It ensured the Blues were able to gain revenge for their defeat to the same side at Fratton Park last Sunday.
Jay Sadler made three changes from the side that won on the road at Chichester & Selsey earlier in the week.
Freya Jones, Emma Jones and Tamsin de Bunsen all returned to the starting line-up, with Anisha Hill, Dani Lane and Hayley Bridge making way.
The visitors had an early opportunity to break the deadlock when de Bunsen found Khassal, whose half-volley cannoned against the crossbar.
Evie Gane then had to be alert at the other end of the pitch, clearing the danger after Tally Miles had diverted a Nicole Pepper free-kick towards the net.
But the Blues were soon back on the attack and a lovely spell of passing play ended with Ava Rowbotham’s shot being tipped against the woodwork.
Both sides were doing their best to break the deadlock and Hannah Haughton came tearing off her line to deny Mollie Coupar and Pepper in quick succession.
It was Pompey who finished the half on top, though, and Chloe Sansom had to save Anaisa Harney’s effort.
Half Time: MK Dons 0 Pompey 0
And the visitors did forge ahead shortly after the interval after Emma Jones had lifted a pass over the Dons defence.
The prolific KHASSAL was able to race onto the ball and lifted it over Sansom from an acute angle.
They were doing a good job of protecting their lead, although Haughton did well to deny Lucy Wood from point-blank range.
Pompey then came close to wrapping up the win when Khassal burst down the wing and found Annie Rolf, who fired into the side netting.
There was still one more chance for the home side to salvage a point and Haughton needed to be at her best to claw away Woods’ angled attempt.
But the Blues were able to see out the contest's closing stages to ensure they would take all three points back to the south coast.
Pompey: Haughton; Quayle, Rowe (c), Gane, McDonnell; Rowbotham, F.Jones (Hill 62), de Bunsen (Rolf 46); E.Jones (Albuery 90), Harney (Younger 88), Khassal (Bridge 82)