Pompey saw off Burton at Fratton Park to register their first League One victory of 2022.
The deserved 2-1 success ensured that the hosts overhauled their opponents in the standings.
Michael Jacobs' corner was headed home by Sean Raggett to break the deadlock in the first half.
And Jacobs then doubled the lead for Danny Cowley's side before Gassan Ahadme pulled one back for the Brewers.
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