Oxford are the final team that Pompey will face this season, with Danny Cowley taking his troops to the Kassam Stadium on Saturday (3pm kick-off).
The sides were supposed to face off on the south coast on Boxing Day, but the match was postponed because of a Covid outbreak.
At that point the Blues were just three points outside the play-off spots, only for that unwanted pause to interrupt momentum.
Now they go in search of a first League One victory of 2022, having dropped down to 12th in the standings.
Their next opponents, meanwhile, are sitting in sixth position following a 1-1 midweek draw at high-flying Wigan.
Immediately before that they had enjoyed a remarkable 7-2 victory at Gillingham, with Cameron Brannagan netting four penalties.
Karl Robinson’s men are looking to make it third time lucky after falling in the play-offs in each of the past two seasons.
Pompey won 1-0 on their last trip to the Kassam Stadium 12 months ago, courtesy of a fine header from Harvey White.
Shaun Williams is set for a spell on the sidelines after suffering a fractured vertebrae, while Jayden Reid (knee) and Liam Vincent (shin) are still injured.
Deadline day signing Aiden O’Brien could make his debut, while Ryan Tunnicliffe is nearing a return to action following a hamstring problem.
Alex Gorrin (knee) and James Henry (calf) are missing for the hosts, who have just added free agent Sam Baldock to their ranks.
HEAD TO HEAD
Pompey: 26 wins
Oxford: 23 wins
On the road
Pompey: 9 wins
Oxford: 19 wins
Referee: Samuel Barrott
Assistants: Joseph Stokes and Paul Kelly
Fourth Official: Carl Brook
Overseas subscribers and match pass holders can watch all the action live, with accompanying commentary.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
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ALSO IN LEAGUE ONE
All games kick-off at 3pm
Burton v Sheffield Wednesday
Charlton v AFC Wimbledon
Ipswich v Gillingham
MK Dons v Lincoln
Morecambe v Bolton
Rotherham v Accrington
Shrewsbury v Fleetwood
Sunderland v Doncaster