Pompey hit five unanswered goals past Aston Villa's under-21 side in the Papa Johns Trophy.
The convincing Fratton Park victory saw the hosts move up to second position in Southern Group B and boost their chances of progressing to the knockout stages.
A fast start saw Ronan Curtis and Michael Jacobs both find the target inside the opening seven minutes.
And Danny Cowley's side struck three more times after the break, with Josh Koroma's brace and a fine Reeco Hackett finish.
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