Fulham U21s have been drawn into Southern Group E of the 2023/24 EFL Trophy.
Pompey will face the Londoners at Fratton Park, with a date for the fixture to be confirmed in due course.
John Mousinho’s men already knew that they would face reigning League Two champions Leyton Orient and fourth tier side Gillingham.
One of those fixtures will take place on home soil and one on the road, with the top two sides qualifying for the knock-out stages.
Bolton are the current EFL Trophy holders after beating Plymouth in last season’s final, while Pompey lifted the silverware in 2019.
Southern Groups
| Group A | Group B | Group C | Group D |
| Forest Green | Charlton | AFC Wimbledon | Cambridge |
| Shrewsbury | Crawley | Stevenage | Colchester |
| Walsall | Sutton | Wycombe | Peterborough |
| Brighton U21 | Aston Villa U21 | Crystal Palace U21 | Tottenham U21 |
| Group E | Group F | Group G | Group H |
| Gillingham | MK Dons | Exeter | Bristol Rovers |
| Leyton Orient | Northampton | Reading | Cheltenham |
| POMPEY | Oxford | Swindon | Newport |
| Fulham U21 | Chelsea U21 | Arsenal U21 | West Ham U21 |
Northern Groups
| Group A | Group B | Group C | Group D |
| Barrow | Crewe | Accrington | Fleetwood |
| Blackpool | Port Vale | Carlisle | Tranmere |
| Morecambe | Wrexham | Harrogate | Wigan |
| Liverpool U21 | Newcastle U21 | Nott'm Forest U21 | Leicester U21 |
| Group E | Group F | Group G | Group H |
| Bolton | Barnsley | Derby | Burton |
| Salford | Bradford | Lincoln | Doncaster |
| Stockport | Grimsby | Notts County | Mansfield |
| Man United U21 | Man City U21 | Wolves U21 | Everton U21 |