Pompey Women make a short trip along the M27 when they visit Cams Alders to take on Moneyfields on Sunday (2pm kick-off).
Attention switches to the National League Cup, with the Blues aiming to secure their place in the second round.
They reached this stage of the competition with an 11-0 rout of Ashford Town in the determining round, which decides whether teams enter the main tournament or drop into the playe.
Jay Sadler's side go into the tie on the back of a comfortable 4-0 success over Oxford at Westleigh Park last weekend.
Dani Lane bagged a brace in the league contest, while Leeta Rutherford and Beth Lumsden were also on the scoresheet.
Moneyfields currently sit sixth in National League South West Divison One – one level below the Blues – having collected nine points from four games.
They beat Torquay in determining round before confiming their spot in round one with a penalty shoot-out victory over QPR.
Ella Wild and Sophie Quirk were on target when the two teams last met, helping Pompey to their latest PDFA Cup triumph back in May.
The game takes place at Cams Alders (PO14 1BJ), with tickets available to buy at the turnstiles.
Supporters at home can keep up to date with the action via the club's social media accounts.
Highlights of the match will be available to watch the following day.