Pompey's run of three consecutive away games continues with a League One trip to Port Vale on Saturday (3pm kick-off).
A return to winning ways against Fleetwood last Saturday, coupled with Derby's midweek loss at Reading, means that John Mousinho's men are still sitting at the top of the table.
Their 18th-placed opponents, meanwhile, will be keen to increase the four-point gap that separates them from the relegation zone.
The Valiants have played the fewest number of fixtures in the division, though, and have as many as three games in hand on the sides below them.
With a contest at Reading abandoned due to supporter protests and a clash with Wycombe falling victim to a frozen pitch, Andy Crosby's outfit have not been in action for three weeks.
Their last outing, on January 6, saw Gavin Massey grab a late leveller in Burslem to secure a 3-3 draw with Charlton.
Dane Scarlett's strike midway through the first half ensured Pompey won last season's corresponding fixture on their first visit to Vale Park for 22 years.
And the Blues also came out on top on home soil earlier in the current campaign, with Colby Bishop bagging a brace in October's 2-0 victory.
TEAM NEWS
Joe Morrell should be fit after taking a nasty knock at Fleetwood, but Joe Rafferty – who missed that match with a stiff neck is a doubt.
Midfielder Myles Peart-Harris could make his Blues bow after completing a loan switch from Brentford earlier in the week.
Tino Anjorin (hamstring), Josh Dockerill (knee), Regan Poole (knee), Alex Robertson (hamstring), Ben Stevenson (knee) and Zak Swanson (groin) are all still sidelined.
Mitch Clark (knee), Ben Garrity (hamstring), Funso Ojo (hamstring) and James Plant (shoulder) are expected to miss out for the hosts, who could hand a debut to new loan signing Dan Gore.
VIEW FROM THE DRESSING ROOM
Read the thoughts of John Mousinho ahead of the game and also see what Peart-Harris had to say about joining Pompey.
HEAD TO HEAD
Overall
Pompey: 20 wins
Port Vale: 9 wins
9 draws
On the road
Pompey: 9 wins
Port Vale: 6 wins
3 draws
TICKETS
Fans can no longer purchase tickets directly from Pompey, but they can be bought (online only) from Port Vale on the day of the game.
OFFICIALS
Referee: Craig Hicks
Assistants: Darren Wilding and Kenwyn Hughes
Fourth Official: Matt Corlett
MATCH COVERAGE
Domestic iFollow subscribers can listen to live commentary from Andrew Moon and Guy Whittingham by signing into their account and visiting the match centre from around 2pm on Saturday.
Overseas subscribers and match pass holders can watch all the action live, with replays and accompanying commentary.
Click here for more information about using iFollow on a matchday and click here for information on downloading the app, so you can access content on your mobile device.
We will have key updates throughout the game on Twitter and a detailed blog via the match centre.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
Local listeners can hear commentary by tuning in to either BBC Radio Solent or Express FM (not available online).
ALSO IN LEAGUE ONE
All games kick-off at 3pm
Barnsley v Exeter
Blackpool v Charlton
Bristol Rovers v Oxford
Cambridge v Burton
Carlisle v Bolton
Derby v Cheltenham
Lincoln v Peterborough
Northampton v Shrewsbury
Reading v Leyton Orient
Wigan v Stevenage
Wycombe v Fleetwood
LAST AWAY MEETING