With the finishing line starting to come into view, Pompey still have quite a few hurdles to negotiate in the race for promotion.
Their next test sees Oxford make the relatively short trip down to Fratton Park on Saturday (3pm kick-off).
The visitors have plenty to play for themselves after dropping out of the play-off places when Stevenage won earlier in the week.
They were tucked in just behind the table-topping Blues when boss Liam Manning departed to take charge of Bristol City back in November.
His replacement Des Buckingham – a former United coach and youth team player – has found wins harder to come by.
The man who led Mumbai City to Indian Super League glory has overseen just five league victories so far, while their last outing was a home defeat to Leyton Orient.
That result ended a six-match unbeaten run which included five draws – beginning with a 2-2 stalemate against Pompey in January.
It was the eighth contest in the past 11 meetings between the sides to end all square, with Colby Bishop and debutant Callum Lang on target that night.
TEAM NEWS
Pompey are waiting for an independent assessment on Connor Ogilvie, who took a blow to the head at Charlton last week.
Defender Zak Swanson is not ready to feature after only recently returning to training following a groin injury.
Tino Anjorin (hamstring), Terry Devlin (shoulder), Josh Dockerill (knee), Tom McIntyre (ankle), Joe Morrell (knee), Regan Poole (knee), Alex Robertson (hamstring) and Ben Stevenson (knee) are still sidelined.
Marcus Browne (hamstring) and Kyle Edwards (hamstring) are the only players missing for Oxford, who are likely to include former Blues loanee Owen Dale in their matchday squad.
VIEW FROM THE DRESSING ROOM
Read the thoughts of John Mousinho and Kusini Yengi ahead of the game.
HEAD TO HEAD
Overall
Pompey: 27 wins
Oxford: 24 wins
24 draws
At Fratton Park
Pompey: 18 wins
Oxford: 4 wins
13 draws
TICKETS
Seats have sold out, but the ticket exchange remains open until 11.59pm on Friday, so keep checking to see if any become available.
If you are coming to the game, click here to find out what is happening around the ground ahead of kick-off.
MATCH COVERAGE
Domestic iFollow subscribers can listen to live commentary from Andrew Moon and Guy Whittingham by signing into their account and visiting the match centre from around 2pm on Saturday.
Overseas subscribers and match pass holders can watch all the action live, with four-camera coverage, replays and accompanying commentary.
Click here for more information about using iFollow on a matchday and click here for information on downloading the app, so you can access content on your mobile device.
We will have key updates throughout the game on Twitter and a detailed blog via the match centre.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Sunday.
Local listeners can hear commentary by tuning in to either BBC Radio Solent or Express FM (not available online).
ALSO IN LEAGUE ONE
All games kick-off at 3pm
Bolton v Cambridge
Carlisle v Reading
Cheltenham v Burton
Derby v Port Vale
Fleetwood v Wigan
Leyton Orient v Bristol Rovers
Lincoln v Stevenage
Northampton v Charlton
Peterborough v Exeter
Shrewsbury v Blackpool
Wycombe v Barnsley
MEMORABLE MEETING
