Pompey switch their attention from gaining points to trying to progress in the Carabao Cup this evening.
After seeing off Championship opponents Cardiff a fortnight ago, there is a quick return to south Wales for Danny Cowley’s side.
This time it is Newport from League Two who stand between the Blues and the next stage of the competition (7.45pm kick-off).
That is where the top-flight clubs competing in Europe enter the competition, which provides an added incentive.
The Exiles also won on the road at a second tier side in round one, twice battling from behind before securing a 3-2 victory at Luton.
James Rowberry’s men are currently sitting 19th in the table, with four points from their opening five games.
Their first success came against Tranmere at Rodney Parade at the weekend and brought welcome relief following three successive defeats.
The sides have not met since Pompey’s triumphant 2016/17 League Two title campaign, with Paul Cook leading them to wins in both clashes that season.
That included a 3-2 triumph in Wales on Boxing Day, which saw the Blues battle back from two goals down to claim the points.
If this evening’s tie finishes level after 90 minutes it will go straight to penalties, with no extra-time being played.
Denver Hume, Joe Morrell and skipper Clark Robertson could all play a part after returning to full fitness.
Jayden Reid (hamstring) and Louis Thompson (leg) are both sidelined, while Colby Bishop is a doubt with a tight quad.
Offrande Zanzala (hamstring) is the only absentee for Newport, with Aaron Wildig and Robbie Willmott shaking off knocks.
HEAD TO HEAD
Pompey: 14 wins
Newport: 13 wins
On the road
Pompey: 6 wins
Newport: 7 wins
Pompey fans can no longer purchase tickets for this game and they will not be sold to visiting fans at the ground this evening.
Collections will be from ‘Gate 6’ at Rodney Parade from 6pm. Please use the postcode NP19 0BH to find this.
Rodney’s Bar in the away end also opens at 6pm and includes a full bar service, as well as large television screens. All bars inside the ground at cashless.
Referee: John Busby
Assistants: Adam Crysell and James Wilson
Fourth Official: Sam Allison
Please note that there is no live video stream of Carabao Cup games on iFollow, including for overseas supporters.
There will be post-match reaction on the website and our official YouTube channel, with highlights to follow on Wenesday.
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ALSO IN CARABAO CUP
Games kick-off at 7.45pm unless stated
Walsall v Charlton (7pm)
Sheffield Wednesday v Rochdale (7.30pm)
Shrewsbury v Burnley (7.30pm)
Barrow v Lincoln
Bolton v Aston Villa
Bradford v Blackburn
Cambridge v Southampton
Colchester v Brentford
Crawley v Fulham
Derby v West Brom
Fleetwood v Everton
Gillingham v Exeter
Grimsby v Nottingham Forest
Norwich v Bournemouth
Oxford v Crystal Palace
Rotherham v Morecambe
Stevenage v Peterborough
Stockport v Leicester
Watford v MK Dons
Wolves v Preston
Forest Green v Brighton
Leeds v Barnsley
Tranmere v Newcastle
Wycombe v Bristol City